After installing the MS14-080 update (KB3008923) for Internet Explorer, the changes made in modal dialog boxes may not be applied when working with the Sitecore Client.
For example, it may not be possible to change the item layout by selecting it from the drop-down list in the Device Editor modal dialog box.
More information about the related update is available here:
https://support.microsoft.com/kb/3008923
Install the appropriate version of the KB3025390 update as described in the following article:
https://support.microsoft.com/kb/3025390