Sitecore Client applications may fail to work properly when the value of the "DisableBrowserCaching" setting is set to "false".
For example, the Content Editor application may fail to save data when editing items. The save action will look like it succeeded but the data will not be saved.
In some other cases, the following error may be raised when using the Content Editor:
[NullReferenceException: Object reference not set to an instance of an object.]
Sitecore.Shell.Applications.ContentManager.ContentEditorForm.OnLoad(EventArgs e)
Set the value of the "DisableBrowserCaching" setting to "true".
<processor type="Sitecore.Pipelines.RenderLayout.BrowserCaching, Sitecore.Kernel" />with
<processor type="Sitecore.Support.Pipelines.RenderLayout.BrowserCaching, Sitecore.Support.312410" />